OPTIMISTIC BUT FLAWED? A REPLY

Vascular risk calculators: essential but flawed clinical tools?

A recent individual participant meta-analysis of statin trials 1 has established beyond reasonable doubt that a patient's pretreatment vascular risk is the most important, easily measureable determinant of the effectiveness of statins. In this meta-analysis, the calculated baseline vascular risk was a much better predictor of absolute treatment benefit than the degree of low-density lipoprotein...

Reply to Blazer et al.: flawed challenges to "Acetylcholinesterase inhibitors and Gulf War illnesses".

thor notes that the following sentences were omitted from the end of the first paragraph of the letter: ''Their statements are counter to fact. They mischaracterize the evidence, employ the introduction of irrelevant material, and exemplify flaws in inference, as I will illustrate.'' The corrected letter appears below. LETTER Reply to Blazer et al.: Flawed challenges to ''Acetylcholinesterase i...

Lissencephaly - A Brain Flawed

We present a case report of a twelve-day old child suffering from seizures, in which magnetic resonance imaging (MRI) established the diagnosis of Lissencephaly. Although the causes of this disease entity are manifold, MRI can reveal stigmata of antenatal maternal infections in the child. In such a scenario, cytomegalovirus (CMV) is an important offender. In this article we discuss the pathogen...

The Authors’ Reply

A traceable optimistic fair exchange protocol in the standard model

An Optimistic Fair Exchange (OFE) protocol is a good way for two parties to exchange their digital items in a fair way such that at the end of the protocol execution, both of them receive their items or none of them receive anything. In an OFE protocol there is a semi-trusted third party, named arbitrator, which involves in the protocol if it is necessary. But there is a security problem when a...